Apeloa Pharmaceutical(000739.SZ): The application for the market approval of Tolterodine Succinate, a chemical raw material for pharmaceuticals, has been approved.

Apeloa Pharmaceutical (000739.SZ) announced that its holding subsidiary, Zhejiang Puluo Kangyu Pharmaceutical Co., Ltd., has received the "Chemical Drug Raw Material Market Approval Notification" issued by the National Medical Products Administration for the approval of the listing of Tenofovir disoproxil fumarate. Tenofovir disoproxil fumarate tablets (trade name: Zepsun) are a Class I innovative drug approved for market by the medical products administration. The holder of the marketing authorization is the company's strategic partner, Suzhou Zejing Biopharmaceutical Co., Ltd. (referred to as "Zejing Pharmaceuticals"). It is used to treat unresectable hepatocellular carcinoma that has not previously undergone systemic therapy, as well as refractory differentiated thyroid cancer that is progressive, locally advanced, or metastatic and difficult to treat with radioactive iodine. The company has signed a research and production services contract with Zejing Pharmaceuticals. The ownership of Tenofovir disoproxil fumarate raw materials approved for market this time belongs to Zejing Pharmaceuticals, and the company does not have ownership, only serving as its raw material producer and supplier.