The Dow Jones Industrial Average fell 0.97% at the opening, the S&P 500 fell 1.3%, and the Nasdaq fell 1.7%.

PepsiCo rose 5.8%, with the aggressive investment firm Elliott Management holding a $4 billion stake in the company. Cytokinetics surged 27.2%, with clinical trials of aficamten showing significant efficacy in treating symptomatic obstructive hypertrophic cardiomyopathy patients. Constellation Brands, a wine company, fell 7.3% after lowering its full-year performance guidance. BEKE rose 2.1%, with several institutions reiterating a "buy" rating after its earnings report.