A new type of kinase inhibitor can effectively combat various emerging viruses.

An international study involving the University of Eastern Finland has found that a novel dual-target lipid kinase inhibitor can effectively combat newly emerging viruses, including various RNA viruses. The research results have been published in the journal "Nature Communications" in the UK. In a recent press release, the University of Eastern Finland stated that during the search for broad-spectrum antiviral drugs, researchers discovered a small molecule inhibitor called RMC-113, which was found to simultaneously inhibit two key lipid kinases, PIKfyve and PIP4K2C, significantly inhibiting the replication of various RNA viruses. RMC-113 demonstrated multiple intervention capabilities in the virus replication process in experiments - not only blocking key pathways that viruses use to replicate within host cells, but also reversing the interference of viruses in the cell's autophagy system, thus inhibiting virus activity on multiple levels.