HK Stock Market Move | BeOne Medicines Ltd. (06160) rose more than 4% in early trading as positive results were achieved in the MANGROVE Phase 3 clinical study. Plans to apply for approval in the second half of the year.
Baiji Shen Zhou (06160) rose more than 4% in early trading, as of the time of writing, it increased by 4.58% to HK $182.7, with a turnover of HK $81.5571 million.
BeOne Medicines Ltd. (06160) rose over 4% in early trading, and as of the time of publication, it has risen by 4.58% to 182.7 Hong Kong dollars, with a trading volume of 81.5571 million Hong Kong dollars.
On the news front, recently, BeOne Medicines Ltd. announced that the MANGROVE 3 clinical trial (BGB-3111-306; NCT04002297) has achieved positive results. This study aims to evaluate the company's independently developed cornerstone product BTK inhibitor zebutinib, in combination with rituximab, compared to bendamustine in combination with rituximab (BR), for the first-line treatment of adult patients with mantle cell lymphoma (MCL).
MANGROVE is the first global, randomized, phase 3 clinical study to evaluate a chemotherapy-free regimen based on BTK inhibitors compared to the standard immunotherapy regimen in this treatment setting. The positive results of this pivotal phase 3 clinical study are expected to strengthen the clinical evidence base for zebutinib in the field of MCL. BeOne Medicines Ltd. plans to announce the complete results of the MANGROVE study at an upcoming medical conference, and is in communication with global regulatory agencies regarding the relevant registration and declaration plans, with plans to submit in the second half of 2026.
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