HK Stock Market Move | METIS TECHBIO-P(07666) has surged by nearly 7% and recently officially released the AiProtein platform and the antibody design intelligent body AARON.

METIS TECHBIO-P (07666) rose by nearly 7%, reaching 4.36% at the time of publication, closing at 13.4 Hong Kong dollars, with a turnover of 21.7154 million Hong Kong dollars. On the news front, recently, according to the official WeChat account of JiTai Technology, the company officially released the AiProtein platform and the antibody design intelligent body AARON. AiProtein adopts JiTai Technology's self-developed "dry experiment + wet experiment + intelligent body" innovation paradigm, focusing on the design platform for large molecules such as proteins and antibodies. As the fourth core solution under JiTai Technology's AI nanocarrier platform NanoForge, AiProtein, along with AiLNP (AI nanocarrier system design platform), AiRNA (AI mRNA sequence design platform), and AiTEM (AI small molecule formulation design platform), jointly completed the end-to-end R&D loop from protein design, mRNA sequence design, and LNP design. It is reported that the AiProtein platform can support AI-driven affinity maturation of antibody lead compounds obtained from screening of animal immune or self-built libraries, and has specially developed the METiS ProteinIFGT anti-folding model, making significant improvements to the industry gold standard ProteinMPNN model. Innovatively introducing the graph Transformer architecture into the protein anti-folding model, there are different degrees of improvement compared to the original model in multiple indicators. On this basis, JiTai further developed the METiS NbIFGT model for nanobody antibodies, together with the aforementioned METiS NbBERT as a double insurance, predicting antibody mutations from two different perspectives to create a new paradigm for antibody engineering.