Shanghai Hile Bio-Technology (603718.SH): Ruiseng Bio's GORORISE absorbable collagen membrane product has obtained approval from the Ministry of Health (MOH).

Shanghai Hile Bio-Technology (603718.SH) announced that its controlling subsidiary, Shaanxi Ruisheng Bio-Technology Co., Ltd. (hereinafter referred to as "Ruisheng Bio"), submitted the registration application materials for its GORORISE Resorbable Collagen Membrane product to the Ministry of Health of Indonesia (MOH) in December 2025. Recently, Ruisheng Bio received notification from MOH that its GORORISE Resorbable Collagen Membrane product has been approved. The GORORISE Resorbable Collagen Membrane, registered in Indonesia this time, is a decellularized extracellular matrix (dECM) material developed and produced by Ruisheng Bio. After tooth loss in clinical patients, the alveolar bone at the missing tooth site often undergoes progressive absorption due to a lack of functional stimulation, resulting in insufficient bone volume for dental implantation. To address this issue, the Resorbable Collagen Membrane is used in conjunction with oral bone filling materials to reconstruct the alveolar bone tissue in the oral implant area of patients with missing teeth, preventing fibroblasts and epithelial cells from invading the soft tissue, providing time and space for slow-growing osteoblasts to enter the bone defect area, and guiding bone tissue/periodontal tissue regeneration.